What Is Exosome Skin Lifting?

Exosome lifting is a non-invasive or minimally invasive facial rejuvenation treatment that uses exosomes—tiny vesicles naturally released by stem cells—to stimulate collagen, elastin, and skin regeneration at a cellular level.

Often applied topically after microneedling, laser, or ultrasound treatments, exosomes help:

• Lift and firm sagging skin
• Smooth fine lines and wrinkles
• Repair damaged or aged skin
• Improve skin tone, texture, and elasticity

What Are Exosomes?

Exosomes are extracellular vesicles released by stem cells that contain growth factors, peptides, RNA, and signaling molecules. These biologically active messengers communicate with skin cells to:

• Accelerate healing
• Reduce inflammation
• Stimulate collagen and elastin production
• Improve skin barrier function and hydration

In cosmetic dermatology, exosomes derived from mesenchymal stem cells (MSC) are most commonly used for facial rejuvenation.

Key Benefits of Exosome Skin Lifting

• Non-surgical alternative to traditional face lifting
• Safe and biocompatible—no artificial chemicals or foreign substances
• Firms and tightens skin by stimulating collagen
• Reduces fine lines, sagging, and dullness
• Enhances recovery when combined with laser, microneedling, or RF treatments
• Boosts overall skin quality and radiance

How Is Exosome Lifting Performed?

Exosomes are typically delivered into the skin using one of the following methods:

1. Microneedling + Exosomes

• Microchannels allow deep penetration of exosomes
• Ideal for skin tightening and scar revision

2. Laser or RF Device + Exosomes

• Energy-based treatments prep the skin
• Exosomes calm inflammation and enhance collagen response

3. Hydro-injection / MTS Pen

• Direct injection or stamping delivers exosomes to targeted areas
• Common for V-line jaw shaping or under-eye firming

4. Topical Application (Post-Treatment)

• Applied after HIFU, Thermage, or Shurink for enhanced results

What Areas Can Be Treated?

• Cheeks and midface
• Jawline and jowls (V-line enhancement)
• Neck and décolletage
• Under-eye area
• Forehead and brow zone
• Full-face rejuvenation

Exosome Skin Lifting vs Other Lifting Treatments

FeatureExosome LiftingThread LiftUltherapy/ThermageMethodCell regenerationPhysical tissue liftDeep tissue tighteningPain / DowntimeNone to mildMild swelling/bruisingMinimal discomfortSkin Quality BoostExcellentModerateModerateLifting PowerSubtle (gradual)StrongModerate to strongIdeal ForSkin texture + mild saggingMid to lower face liftMild to moderate laxity

Pro tip: Exosomes are often used with other lifting treatments to enhance skin regeneration and healing.

How Long Do Results Last?

• Results begin appearing in 2–4 weeks
• Full effects develop over 6–12 weeks
• Collagen and elastin stimulation can continue for 4–6 months
• Maintenance every 3–6 months is ideal for long-term skin health

Are There Any Side Effects?

Exosome therapy is very safe, especially when using high-quality, sterile lab-cultured exosomes. Possible side effects are rare but may include:

• Mild redness or swelling (especially after microneedling or lasers)
• Temporary sensitivity
• Slight bruising (if injected)

Always choose a board-certified dermatologist or aesthetic provider using medically approved exosome products.

Exosome Skin Lifting Cost (Estimated)

Treatment TypeKorea (₩)Approx. USDMicroneedling + Exosomes₩300K – ₩800K$230 – $600RF/Laser + Exosomes₩500K – ₩1.2M$400 – $900Hydro-Stamp Injection₩700K – ₩1.5M$500 – $1,100Full-Face Packages₩1M – ₩2.5M$750 – $1,900

Pricing varies based on method, exosome brand, and clinic reputation.



Exosome skin lifting is a breakthrough in regenerative aesthetics. By harnessing the healing power of stem cell-derived exosomes, this treatment offers natural lifting, collagen production, and overall skin rejuvenation—without needles, scars, or toxins.

It’s ideal for patients seeking a glow-up with long-term benefits, either on its own or as part of a combo program with microneedling, laser, or ultrasound lifting.